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Nursing Degree in St. Louis, MO — Salary & ROI 2026

Nursing degree analysis for St. Louis, MO. COL-adjusted salary data, local tuition costs, ROI calculator, and job market outlook.

Starting Salary

$66K

COL-adjusted

Mid-Career

$80K

COL-adjusted

ROI Payback

2.6 yrs

in St. Louis

Cost of Living

97

index (100 = avg)

Nursing in St. Louis, MO Overview

St. Louis is one of Missouri's top college towns, with 23 institutions and a student population of 23,342. Public tuition averages $12,343/year here — near the national average for public universities. Nursing has seen growing enrollment nationally, reflecting rising employer demand for Patient Care and Clinical Assessment skills. The adjusted starting salary in St. Louis is approximately $65,960.

Category

Healthcare

Local Colleges

23

Public Tuition

$12,343/yr

Private Tuition

$55,255/yr

Room & Board

$8,721/yr

Avg Fin. Aid

$9,996/yr

Unemployment

4.5%

Graduation Rate

48%

Nursing Salary in St. Louis (COL-Adjusted)

Salaries adjusted for St. Louis's cost of living index of 97 (national average = 100).

Entry Level (0-2 yrs)
$65,960($-2,040 vs national)
Mid Career (5-9 yrs)
$79,540($-2,460 vs national)
Senior Level (15+ yrs)
$92,150($-2,850 vs national)

Note: National average Nursing salary: $68,000 starting, $82,000 mid-career, $95,000 senior level.St. Louis adjustment factor: 0.97x based on the local cost of living index.

Nursing ROI Calculator for St. Louis

Estimate your return on investment for a Nursing degree using local St. Louis tuition and cost of living data.

Public avg: $12,343 | Private avg: $55,255

St. Louis avg aid: $9,996/yr

Federal avg: 6.5% | Private: 4-14%

Total Education Cost

$84,256

tuition + room & board - aid

Annual Earnings Premium

$32,010

vs HS diploma in St. Louis

ROI Payback Period

2.6 years

to break even

Lifetime Return in St. Louis

$594,744

Lifetime earnings premium ($679,000) minus total education cost ($84,256)

Student Loan Payoff for Nursing in St. Louis

Standard Plan (10 years)

Loan Amount$84,256
Monthly Payment$957
Total Interest$30,549
% of Monthly Income17%

Aggressive Plan (5 years)

Loan Amount$84,256
Monthly Payment$1,649
Total Interest$14,658
Interest Savings$15,891

Colleges in St. Louis for Nursing

Washington University in St. Louis

private

$60,590/yr

$242,360 total

Saint Louis University

private

$49,920/yr

$199,680 total

Community Colleges (2-Year Transfer)

St. Louis Community College

$3,600/yr

Top Employers for Nursing in St. Louis

St. Louis offers opportunities in Hospitals, Medical centers, Private practices for Nursing graduates. National top employers in this field include:

HCA HealthcareKaiser PermanenteMayo ClinicCleveland ClinicVA Hospitals

Key St. Louis Hiring Sectors for Healthcare

Hospitals

Medical centers

Private practices

Health systems

Pharma companies

Common Nursing Job Titles

Registered NurseNurse PractitionerClinical Nurse Specialist

Nursing Degree in St. Louis — FAQ

Data Sources: Salary data from BLS Occupational Outlook Handbook. Cost of living from BLS Regional Data. College data from NCES/IPEDS. Updated March 2026.

Explore More

Compare Nursing ROI in other cities, or explore other majors in St. Louis.

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